A few strange ones.

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Seems targeted.  Telling me something?  Asking?  I... definitely get a vibe.

The gifts of Ruin?  I know these.  I know that one.  I will... know more.  Doomed?  Of flesh.  Always doomed, forever.  If only of this flesh.  Should that be the choice.

Drink opium?  I... will skip.  I have grown quite fond of my crosses, and pain.

As to a response?  Well... take your pick.

In truth, you will get a twofer.  Should you choose either.  It comes, whichever way you choose.  Relax and enjoy or prepare for the cataclysm.